NCT06937528 Use of Extracellular Vesicles (EV) for Knee Osteoarthrosis
| NCT ID | NCT06937528 |
| Status | Recruiting |
| Phase | Phase 1 |
| Sponsor | University of Jordan |
| Condition | Knee Osteoarthrosis |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2026-01-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
Phase 1 is the earliest stage of human testing — safety and dosage are the primary focus. Visits are frequent and medical supervision is intensive. You will be among the first people to receive this treatment.
This trial targets 50 participants in total. It began in 2024-01-01 with a primary completion date of 2026-01-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Extracellular vesicles (EV) will be injected in patients diagnosed with Knee osteoarthrosis
Eligibility Criteria
Inclusion Criteria: * Severe KOA stage III or IV by Laurance \& Kellgren staging as judged by Posterioranterior (PA) Xray of the knee joint. * Willing to participate by signing the informed consent Exclusion Criteria: * Sublaxation beyond 20 degrees of the bones of the knee joint * Oral anticoagulants or heparin therapy * Heart failure or arrhythmia * Body Mass Index \> 35 * Uncontrolled Diabetes Mellitus. * Evidence of Infectious Diseases. * Active infection * Malignancy * Pregnancy * Anemia less than 11g/dl or thrombocytopenia less than 100,000 or leucopenia less than 3000. * Unreliable patients * Non-resident in Jordan
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06937528 clinical trial?
This trial is open to participants of all sexes, aged 42 Years or older, up to 75 Years, studying Knee Osteoarthrosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
What phase is the NCT06937528 trial and what does that mean for participants?
Phase 1 trials are the first stage of human testing. The primary goal is to assess safety and determine appropriate dosage levels. Participants are closely monitored. These trials typically involve a small number of volunteers.
Is NCT06937528 currently recruiting?
Yes, NCT06937528 is actively recruiting participants. Contact the research team at hanan.jafar@gmail.com for enrollment information.
Where is the NCT06937528 trial being conducted?
This trial is being conducted at Amman, Jordan.
Who is sponsoring the NCT06937528 clinical trial?
NCT06937528 is sponsored by University of Jordan. The trial plans to enroll 50 participants.