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Recruiting Phase 2 NCT06164613

Use of Cinnamomum Verum for Induction of Labor. Double Blind Randomized Clinical Trial

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Trial Parameters

Condition Labor Onset and Length Abnormalities
Sponsor Universidad Nacional Autonoma de Honduras
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 70
Sex FEMALE
Min Age 14 Years
Max Age 45 Years
Start Date 2023-12-04
Completion 2026-12-30
Interventions
Cinnamomum Verum oil extractPlacebo

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Brief Summary

The purpose of the research protocol is to evaluate the effectiveness of Cinnamomum verum extract for the initiation of labor. Cinnamaldehyde ((E)-3-Phenylprop-2-enal) is an α, β unsaturated aromatic aldehyde, derived from cinnamon (Cinnamomum Verum oil) used as a flavoring; It is a clear yellowish liquid substance, with a strong odor and flavor. It is the main component of cinnamon (63%), giving it its physicochemical properties. Cinnamon has been an element of empirical use for the beginning of labor, however, its effectiveness has not been demonstrated. Cinnamon has been reported for its ethnopharmacological properties in pregnancy, being used to facilitate childbirth, as a lactagogue and for postpartum recovery. In Honduras, its use has been reported to relieve nausea and vomiting during pregnancy, to reduce abdominal pain. , reduction of lower limb edema, to relieve anxiety during labor, as well as a lactagogue without convergent opinions.

Eligibility Criteria

Inclusion Criteria: 1. Delivery of an informed consent form signed and dated by parents or guardian and patient 2. Declared willingness to comply with all study procedures and availability for the duration of the study. 3. provision of appropriate consent and assent 4. Willingness and ability to participate in study procedures 5. Patients under 18 years of age 6. Full-term pregnancies (37-41 Weeks of Gestation). 7. Nulliparity 8. Have your own cell phone 9. Know how to read and write 10. Residing in Tegucigalpa 11. Be in good general health, as evidenced by your medical history 12. Ultrasound with amniotic fluid index \> 5 cm 13. Non Stress Test Reactive 14. Ability to take oral medication and be willing to comply with the cinnamon capsule regimen Exclusion Criteria: 1. Current use of antihypertensive or hypoglycemic medications 2. Presence of non-curable chronic diseases prior to pregnancy or during pregnancy such as hypertension, diabetes, hypothyroidism 3. Premature rupture of membr

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