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Recruiting EARLY_Phase 1 NCT04026776
NCT04026776 Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
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Plain-language summary for patients
| NCT ID | NCT04026776 |
| Status | Recruiting |
| Phase | EARLY_Phase 1 |
| Sponsor | Wake Forest University Health Sciences |
| Condition | Salt; Excess |
| Study Type | INTERVENTIONAL |
| Enrollment | 120 participants |
| Start Date | 2020-09-02 |
| Primary Completion | 2026-06 |
Trial Parameters
Condition Salt; Excess
Sponsor Wake Forest University Health Sciences
Study Type INTERVENTIONAL
Phase EARLY_Phase 1
Enrollment 120
Sex ALL
Min Age 22 Years
Max Age 33 Years
Start Date 2020-09-02
Completion 2026-06
All Conditions
Interventions
AllopurinolDietary Intervention
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Brief Summary
The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.
Eligibility Criteria
Inclusion Criteria: * Singleton birth * Born at less than 34 weeks gestational age (preterm cohort) * Born at greater than 36 weeks gestational age (term cohort) Exclusion Criteria: * Twin birth * Congenital anomalies or genetic syndromes * Currently pregnant or breast feeding * Subject-reported history of hypertension * Current use of antihypertensive medications * Active cancer * Chronic kidney disease * Heart failure * Liver failure
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