NCT06799832 Urethral PeRfusion Index-Guided Hemodynamic ManagemenT in Patients Having Major Abdominal Surgery: the UPRIGHT Randomized Feasibility Trial
| NCT ID | NCT06799832 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Universitätsklinikum Hamburg-Eppendorf |
| Condition | Urethral Perfusion Index |
| Study Type | INTERVENTIONAL |
| Enrollment | 116 participants |
| Start Date | 2025-01-21 |
| Primary Completion | 2025-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 116 participants in total. It began in 2025-01-21 with a primary completion date of 2025-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
We will perform this single-center pilot trial to determine if the intraoperative urethral perfusion index is higher in patients assigned to maintaining postinduction baseline urethral perfusion index than in patients assigned to routine care (with blinded urethral perfusion index monitoring). As pre-planned substudies, we will also assess the agreement between a) urethral perfusion index-derived pulse rate and heart rate measured with an electrocardiogram and b) between the urethral perfusion index and the peripheral perfusion index.
Eligibility Criteria
Inclusion Criteria: * at least 45 years old * scheduled for elective major abdominal surgery (involving visceral organs with an expected duration of at least 120 minutes) * indication for an arterial catheter * indication for an urinary catheter Exclusion Criteria: * Pregnancy * Planned surgery: nephrectomy, liver or kidney transplantation surgery * Patients who previously had surgery on the urethra or bladder * Patients without clinical indication for continuous blood pressure monitoring with an intraarterial catheter
Contact & Investigator
Bernd Saugel, MD
PRINCIPAL INVESTIGATOR
University Medical Center Hamburg Eppendorf, Hamburg, Germany and OUTCOMES RESEARCH Consortium®, Houston, Texas, USA
Frequently Asked Questions
Who can join the NCT06799832 clinical trial?
This trial is open to participants of all sexes, aged 45 Years or older, studying Urethral Perfusion Index. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06799832 currently recruiting?
Yes, NCT06799832 is actively recruiting participants. Contact the research team at b.saugel@uke.de for enrollment information.
Where is the NCT06799832 trial being conducted?
This trial is being conducted at Hamburg, Germany, Hamburg, Germany.
Who is sponsoring the NCT06799832 clinical trial?
NCT06799832 is sponsored by Universitätsklinikum Hamburg-Eppendorf. The principal investigator is Bernd Saugel, MD at University Medical Center Hamburg Eppendorf, Hamburg, Germany and OUTCOMES RESEARCH Consortium®, Houston, Texas, USA. The trial plans to enroll 116 participants.