NCT06471387 Unraveling the Genetic Basis of Nicotine Addiction for Novel Therapeutic Strategies
| NCT ID | NCT06471387 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Cyprus |
| Condition | Smoking Cessation |
| Study Type | OBSERVATIONAL |
| Enrollment | 200 participants |
| Start Date | 2023-11-01 |
| Primary Completion | 2025-10-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 200 participants in total. It began in 2023-11-01 with a primary completion date of 2025-10-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This case-control study aims to investigate the genetic and molecular bases of nicotine addiction to identify potential therapeutic targets. The project will involve drug repurposing using Mendelian Randomization, a smoking cessation intervention, and the analysis of methylation status in participants undergoing nicotine withdrawal.
Eligibility Criteria
Inclusion Criteria: * Adults aged 18-60 years old * Current daily cigarette smoker * Able to understand study procedures and provide informed consent * For females, non-pregnant and non-lactating Exclusion Criteria: * Presence of significant uncontrolled medical conditions (e.g. cardiovascular disease, respiratory disorders, cancer) that could affect smoking behaviors or study participation * Presence of major uncontrolled psychiatric disorders (e.g. schizophrenia, bipolar disorder, severe depression) * Current substance use disorder (except nicotine dependence) * Taking medications that could significantly interfere with study objectives (e.g. medications for smoking cessation) * Significant cognitive impairment that precludes ability to complete study procedures
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06471387 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Smoking Cessation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06471387 currently recruiting?
Yes, NCT06471387 is actively recruiting participants. Contact the research team at georgiou.andrea@ucy.a.cy for enrollment information.
Where is the NCT06471387 trial being conducted?
This trial is being conducted at Nicosia, Cyprus.
Who is sponsoring the NCT06471387 clinical trial?
NCT06471387 is sponsored by University of Cyprus. The trial plans to enroll 200 participants.