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Recruiting NCT06334588

Understanding the Mechanisms of Autism : an MRI and Social Cognition Study

Trial Parameters

Condition Autism Spectrum Disorder
Sponsor Assistance Publique - Hôpitaux de Paris
Study Type INTERVENTIONAL
Phase N/A
Enrollment 160
Sex ALL
Min Age 3 Months
Max Age 28 Years
Start Date 2024-04-17
Completion 2029-04
Interventions
MRIEye-trackingClinical Scales

Brief Summary

The main goal of this study is to investigate anatomo-functional brain abnormalities associated with autism spectrum disorders using a multimodal brain imaging approach, as well as its links to social cognition difficulties measured using eye-tracking

Eligibility Criteria

Inclusion Criteria: For subjects diagnosed with ASD or suspected of ASD : * 3 months ≤ age \< 25 years ; * an MRI required as part of the clinical procedures * written consent obtained from parents or legal guardians. * Affiliated to social security For Healthy control subjects over 3 years of age: * between 3 and 28 years of age * no known neurological or psychiatric pathology * written consent obtained from parents or legal guardian. * Affiliated to social security For Healthy control subjects under 5 years of age: * age between 3 months and 5 years * who have had an MRI scan in the pediatric radiology department at Necker Hospital, which was found to be normal. * with no known neurological or psychiatric pathology * no opposition from legal representative Exclusion Criteria: * Contraindication to MRI (pacemaker, intracorporeal metallic body, claustrophobia). * Impossibility for healthy volunteers to remain still during MRI

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