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Recruiting NCT05065151

NCT05065151 Understanding Motivation in Parkinson's Patients Through Neurophysiology

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Clinical Trial Summary
NCT ID NCT05065151
Status Recruiting
Phase
Sponsor University of California, San Francisco
Condition Parkinson Disease
Study Type INTERVENTIONAL
Enrollment 70 participants
Start Date 2021-10-30
Primary Completion 2030-12-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Stimulation onStimulation offDecision Making Task

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 70 participants in total. It began in 2021-10-30 with a primary completion date of 2030-12-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The study aims to better understand motivation and value-based decision-making in Parkinson's patients through neurophysiology using Medtronic's Percept DBS device. By combining behavioral tasks with neural recordings, the study seeks to uncover how DBS affects motivation, particularly in relation to effort, reward, and timing.

Eligibility Criteria

Inclusion Criteria: * Has Parkinson's Disease or Dystonia * Has Medtronic Percept or RC+S DBS device implanted in either GPI or STN * Has DBS device implanted either bilaterally or unilaterally * Male or female * More than 1 month post-DBS surgery Exclusion Criteria: * Severe cognitive impairments * Has MOCA score below 20 * Pregnancy * Age less than 18 years old

Contact & Investigator

Central Contact

Sarah Wang, PhD

✉ Sarah.Wang@ucsf.edu

📞 415-353-7885

Principal Investigator

Simon J Little, MBBS, PhD

PRINCIPAL INVESTIGATOR

University of California, San Francisco

Frequently Asked Questions

Who can join the NCT05065151 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Parkinson Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05065151 currently recruiting?

Yes, NCT05065151 is actively recruiting participants. Contact the research team at Sarah.Wang@ucsf.edu for enrollment information.

Where is the NCT05065151 trial being conducted?

This trial is being conducted at San Francisco, United States.

Who is sponsoring the NCT05065151 clinical trial?

NCT05065151 is sponsored by University of California, San Francisco. The principal investigator is Simon J Little, MBBS, PhD at University of California, San Francisco. The trial plans to enroll 70 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology