NCT06007404 Understanding Metabolism and Inflammation Risks for Diabetes in Adolescents
| NCT ID | NCT06007404 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Michigan |
| Condition | Type 2 Diabetes |
| Study Type | OBSERVATIONAL |
| Enrollment | 175 participants |
| Start Date | 2023-09-06 |
| Primary Completion | 2027-09 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 175 participants in total. It began in 2023-09-06 with a primary completion date of 2027-09.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research study collects health-related information and blood samples to better understand how body composition, lifestyle habits, and diet influence meta-inflammatory monocytes (MiMos) in adolescents. The hypothesis of this study is that adolescents at risk for metabolic disease have enhanced MiMo related activities leading to insulin resistance.
Eligibility Criteria
Inclusion Criteria: * Between 14 and 18 years of age * Tanner stage 4 or 5 (mature adult stage of puberty) * Normal weight (BMI ≥ 5th percentile \& \< 85th percentile), overweight (BMI \> 86th percentile) \& \< 94th percentile), obese weight (BMI percentile ≥ 95th percentile), and/or pre-diabetes (HbA1c \> 5.7%) * For Type 2 Diabetes cohort, diagnosis of Type 2 Diabetes Exclusion Criteria: * Currently pregnant * Use medications known to affect glucose metabolism (immunosuppressive medications, cancer medications, or high dose steroids), unless prescribed for Type 2 Diabetes management * Prior diagnosis of autoimmune disease, cancer, or a cognitive or perceptual disability that would inhibit following directions of study staff * Allergies or intolerance to milk, soy, or palm oil
Contact & Investigator
Kanakadurga Singer, MA, MD
PRINCIPAL INVESTIGATOR
University of Michigan
Frequently Asked Questions
Who can join the NCT06007404 clinical trial?
This trial is open to participants of all sexes, aged 14 Years or older, up to 18 Years, studying Type 2 Diabetes. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06007404 currently recruiting?
Yes, NCT06007404 is actively recruiting participants. Contact the research team at MiMoStudy@med.umich.edu for enrollment information.
Where is the NCT06007404 trial being conducted?
This trial is being conducted at Ann Arbor, United States.
Who is sponsoring the NCT06007404 clinical trial?
NCT06007404 is sponsored by University of Michigan. The principal investigator is Kanakadurga Singer, MA, MD at University of Michigan. The trial plans to enroll 175 participants.
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