NCT06153888 ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study
| NCT ID | NCT06153888 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Umeå University |
| Condition | Fluid Overload |
| Study Type | INTERVENTIONAL |
| Enrollment | 40 participants |
| Start Date | 2023-03-20 |
| Primary Completion | 2026-03-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 40 participants in total. It began in 2023-03-20 with a primary completion date of 2026-03-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD. The length of HD is usually the same as the time of fluid removal while sometimes this may differ. There is no clear guideline. In previous research the investigator noted that the heart releases more NT-pro-BNP during HD in numerous of the patients. The present study aims to clarify if the speed of fluid removal during HD is a factor that may alter the release of cardiac markers during HD. If so the recommendations for the prescription of HD can be updated.
Eligibility Criteria
Inclusion Criteria: * Adult HD patients with an intra-dialytic weight gain (IDWG) ≥2.5% of target weight over the long interval (3 days) prior to inclusion. * Patients need to be able to understand the study information * Patients need to be able to give consent. Exclusion Criteria: * Active systemic inflammatory state such as extensive malignancy or acute septic infection. * Uncontrolled hyperphosphatemia decided by the local routine of the physician (due to somewhat decreased efficacy of the low flux filter to eliminate phosphate)
Contact & Investigator
Bernd Stegmayr, MD, PhD
PRINCIPAL INVESTIGATOR
Umea University, Umea, Sweden
Frequently Asked Questions
Who can join the NCT06153888 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Fluid Overload. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06153888 currently recruiting?
Yes, NCT06153888 is actively recruiting participants. Contact the research team at bernd.stegmayr@umu.se for enrollment information.
Where is the NCT06153888 trial being conducted?
This trial is being conducted at Umeå, Sweden.
Who is sponsoring the NCT06153888 clinical trial?
NCT06153888 is sponsored by Umeå University. The principal investigator is Bernd Stegmayr, MD, PhD at Umea University, Umea, Sweden. The trial plans to enroll 40 participants.