NCT06336941 "Ultra-High Frequency intraOral UltraSonography of the TONgue" (HOUSTON)
| NCT ID | NCT06336941 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Pisa |
| Condition | Oral Squamous Cell Carcinoma |
| Study Type | INTERVENTIONAL |
| Enrollment | 400 participants |
| Start Date | 2018-06-07 |
| Primary Completion | 2025-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 400 participants in total. It began in 2018-06-07 with a primary completion date of 2025-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Oral diseases are currently diagnosed by means of clinical examination and supported by surgical biopsy procedures. In particular, daily oral medicine practice is lacking the use of a routine diagnostic support to the visualization of anatomical structures located beyond the mucosal surface. Considering the growing interest in minimally invasive diagnosis, the possibility of having an imaging technique dedicated to the investigation of oral soft tissues and their alterations may be instrumental to support the clinical diagnosis. Therefore, attempts to introduce conventional ultrasonography (US) to the diagnostic work-up of pathological conditions of the head and neck have been done, exploiting the unique features of this technique in terms of limited invasive- ness, repeatability, and cost efficiency. In the literature, both extraoral and intraoral applications of US have been reported. Extraoral applications mainly focus on the characterization of oral and maxillofacial swellings of various origin, while intraoral applications mostly involve the study of malignant lesions in terms of tumor thickness and depth of invasion. The aim of the present protocol is to evaluate the role of intraoral ultra-high frequency ultrasonography in the study of oral mucosal lesions.
Eligibility Criteria
Inclusion Criteria: * Clinical diagnosis of oral squamous cell carcinoma * Eligibility for surgical treatment * Acceptance to be included in the study Exclusion Criteria: * Oral lesions other than oral squamous cell carcinoma * Pregnant or breastfeeding patients * Uncontrolled chronic diseases and/or conditions hindering the participation in the study * Denial of inclusion in the study
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06336941 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Oral Squamous Cell Carcinoma. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06336941 currently recruiting?
Yes, NCT06336941 is actively recruiting participants. Contact the research team at rossana.izzetti@unipi.it for enrollment information.
Where is the NCT06336941 trial being conducted?
This trial is being conducted at Pisa, Italy.
Who is sponsoring the NCT06336941 clinical trial?
NCT06336941 is sponsored by University of Pisa. The trial plans to enroll 400 participants.