NCT07454447 UBM Evaluation After Combined Deep Sclerectomy With Trabeculotomy in Primary Open Angle Glaucoma
| NCT ID | NCT07454447 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Minia University Hospital |
| Condition | Primary Open Angle Glaucoma (POAG) |
| Study Type | OBSERVATIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-11-11 |
| Primary Completion | 2026-11 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 30 participants in total. It began in 2025-11-11 with a primary completion date of 2026-11.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Primary open-angle glaucoma is a chronic optic neuropathy that often requires surgical intervention when medical treatment fails. Deep sclerectomy is a non-penetrating glaucoma surgery that aims to reduce intraocular pressure while minimizing complications. When combined with trabeculotomy, additional aqueous outflow may be achieved. Ultrasound biomicroscopy (UBM) allows detailed imaging of the anterior segment and provides valuable information about postoperative anatomical changes that cannot be assessed clinically. This observational study aims to evaluate UBM findings after combined deep sclerectomy with trabeculotomy in patients with primary open-angle glaucoma and to correlate these findings with clinical outcomes.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of primary open-angle glaucoma (POAG), including juvenile open-angle glaucoma (JOAG). * Patients who underwent combined deep sclerectomy with trabeculotomy. * Clear media allowing adequate ultrasound biomicroscopy imaging. * Written informed consent obtained from the patient . Exclusion Criteria: * Secondary glaucomas (e.g., neovascular, uveitic, traumatic, or angle-closure glaucoma). * Previous glaucoma filtering surgery in the studied eye. * Coexisting ocular pathology affecting UBM assessment (e.g., severe corneal opacity, scleral pathology).
Frequently Asked Questions
Who can join the NCT07454447 clinical trial?
This trial is open to participants of all sexes, studying Primary Open Angle Glaucoma (POAG). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07454447 currently recruiting?
Yes, NCT07454447 is actively recruiting participants. Visit ClinicalTrials.gov or contact Minia University Hospital to inquire about joining.
Where is the NCT07454447 trial being conducted?
This trial is being conducted at Minya, Egypt.
Who is sponsoring the NCT07454447 clinical trial?
NCT07454447 is sponsored by Minia University Hospital. The trial plans to enroll 30 participants.