NCT07502586 Turner Syndrome: Genetic Considerations
| NCT ID | NCT07502586 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) |
| Condition | Genetic |
| Study Type | OBSERVATIONAL |
| Enrollment | 500 participants |
| Start Date | 2026-03-24 |
| Primary Completion | 2027-08-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 500 participants in total. It began in 2026-03-24 with a primary completion date of 2027-08-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Background: Turner syndrome (TS) is a rare genetic condition. It happens when a person is born missing all or part of an X sex chromosome. People with TS can have heart defects, short stature, autoimmune conditions, and malformations. Many women with TS never have periods and cannot conceive; however, some women have normal ovaries (egg cells). Researchers want to learn more about why some women with TS are fertile and others are not. To do this, they need to be able to compare the genes of many women who have TS. Objective: To create a genetic database of people with TS. Eligibility: People of any age with TS. Biological parents and other relatives are also needed. Design: Participants who agree to join this study will be asked to enroll in a second study; that study is called NIAID Centralized Sequencing Protocol (Protocol No. 17I0122). Participants will have 1 study visit. They may fill out a survey or do an interview. They will provide blood, saliva, or other tissue samples. Those samples will be used for genetic tests. The visit will take 1 hour. The information collected in those tests will be collected for use in the database created as part of this study.
Eligibility Criteria
* INCLUSION CRITERIA: 1. Turner syndrome diagnosis based on karyotype 2. Any age 3. Biological parent of Turner syndrome patient 4. Relatives of Turner syndrome patient 5. The subject from protocol 20CH0126 will enroll in this study only when they agree to be referred to the 17I0122 NIAID study. They can withdraw participation in the 17I0122 study if they do not want to have their genetic data in this database EXCLUSION CRITERIA: 1\. Diagnosis other than Turner syndrome
Contact & Investigator
Veronica Gomez-Lobo, M.D.
PRINCIPAL INVESTIGATOR
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Frequently Asked Questions
Who can join the NCT07502586 clinical trial?
This trial is open to participants of all sexes, aged 1 Day or older, up to 110 Years, studying Genetic. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07502586 currently recruiting?
Yes, NCT07502586 is actively recruiting participants. Contact the research team at veronica.gomez-lobo@nih.gov for enrollment information.
Where is the NCT07502586 trial being conducted?
This trial is being conducted at Bethesda, United States.
Who is sponsoring the NCT07502586 clinical trial?
NCT07502586 is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The principal investigator is Veronica Gomez-Lobo, M.D. at Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The trial plans to enroll 500 participants.