NCT07088952 Triggering Ovulation at Follicle Size Smaller or Larger Than 17mm in a Modified Natural Cycle
| NCT ID | NCT07088952 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Vida Recoletas Sevilla |
| Condition | Embryo Transfer |
| Study Type | INTERVENTIONAL |
| Enrollment | 572 participants |
| Start Date | 2025-10-22 |
| Primary Completion | 2027-07-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 572 participants in total. It began in 2025-10-22 with a primary completion date of 2027-07-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The rise in frozen embryo transfer (FET) cycles within assisted reproductive technology (ART) has sparked the need to refine endometrial preparation protocols. The switch from hormone replacement cycles (HRT) to natural cycles, poses scheduling challenges onto laboratories, doctors and patients. The modified natural cycle (mNC), offering more precision for scheduling, shows promise but lacks comprehensive data on the potential flexibility of triggering criteria that may allow to control timing in a wider range. This prospective randomized study seeks to address this knowledge gap by evaluating the non-inferiority of triggering ovulation in mNC with follicle diameters of 13-16.9mm compared to the conventional 17-22mm. The study aims to enhance the understanding of the impact of follicle size at ovulation in reproductive outcomes, optimize FET treatments providing a more flexible mNC protocol, and improve patient care in ART clinics.
Eligibility Criteria
Inclusion Criteria: * At least one expanded blastocyst (regardless of its quality) * Spontaneous menstrual cycles * Consent to undergo frozen embryo transfer in a modified natural cycle Exclusion Criteria: * Abnormal uterine cavity * Fluid in endometrial cavity
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07088952 clinical trial?
This trial is open to female participants only, aged 18 Years or older, up to 50 Years, studying Embryo Transfer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07088952 currently recruiting?
Yes, NCT07088952 is actively recruiting participants. Contact the research team at vida.investiga@gruporecoletas.com for enrollment information.
Where is the NCT07088952 trial being conducted?
This trial is being conducted at Seville, Spain.
Who is sponsoring the NCT07088952 clinical trial?
NCT07088952 is sponsored by Vida Recoletas Sevilla. The trial plans to enroll 572 participants.