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Recruiting NCT04239703

NCT04239703 Trifecta-Kidney cfDNA-MMDx Study

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Clinical Trial Summary
NCT ID NCT04239703
Status Recruiting
Phase
Sponsor University of Alberta
Condition Kidney Transplant Rejection
Study Type OBSERVATIONAL
Enrollment 300 participants
Start Date 2019-12-01
Primary Completion 2028-12

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age N/A
Study Type OBSERVATIONAL
Interventions
MMDxProsperaHLA antibody

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 300 participants in total. It began in 2019-12-01 with a primary completion date of 2028-12.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Demonstrate the relationship between DD-cfDNA levels and HLA antibodies in blood, and the Molecular Microscope® (MMDx) Diagnostic System results in indication biopsies.

Eligibility Criteria

Inclusion Criteria: * All kidney transplant recipients undergoing a kidney biopsy for clinical indications, as determined by their physician or surgeon, will be eligible to enroll in the study. Exclusion Criteria: * Patients will be excluded from the study if they decline participation or are unable to give informed consent or multiple organ recipients.

Contact & Investigator

Central Contact

Konrad S Famulski, PhD

✉ konrad@ualberta.ca

📞 1 780 492 1725

Principal Investigator

Philip F Halloran, MD, PhD

PRINCIPAL INVESTIGATOR

University of Alberta

Frequently Asked Questions

Who can join the NCT04239703 clinical trial?

This trial is open to participants of all sexes, studying Kidney Transplant Rejection. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04239703 currently recruiting?

Yes, NCT04239703 is actively recruiting participants. Contact the research team at konrad@ualberta.ca for enrollment information.

Where is the NCT04239703 trial being conducted?

This trial is being conducted at Tampa, United States, Baltimore, United States, Baltimore, United States, Detroit, United States and 11 additional locations.

Who is sponsoring the NCT04239703 clinical trial?

NCT04239703 is sponsored by University of Alberta. The principal investigator is Philip F Halloran, MD, PhD at University of Alberta. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology