Trial of Ovarian Vein and Pelvic Vein Embolization in Women With Chronic Pelvic Pain and Pelvic Varices
This study tests whether a procedure called embolization (blocking ovarian and pelvic veins) can help women with chronic pelvic pain caused by varicose veins in the pelvis. Researchers will compare women who receive the embolization procedure to women who only receive imaging (venography) to see which approach works better for reducing pain and improving quality of life.
Key Objective: The trial tests whether embolizing (blocking) problem pelvic veins can reduce chronic pelvic pain and improve quality of life in women with pelvic varices.
Who to Consider: Women with chronic pelvic pain and confirmed pelvic varicose veins who want to explore a minimally invasive treatment option should consider enrolling.
Trial Parameters
Brief Summary
The purpose of this study is to see if a randomized controlled trial of ovarian vein and pelvic vein embolization versus venography alone could determine outcomes for women with chronic pelvic pain and pelvic varicose veins. The data gathered will assist in addressing changes in quality of life in patients who have ovarian/pelvic vein embolization versus no embolization.
Eligibility Criteria
Inclusion Criteria: 1. Presence of venous origin chronic pelvic pain for greater than 6 months (VAS ≥7 as determined by 4 consecutive weeks of baseline self-assessments) despite non-vascular therapy as delineated by the following criteria: * Pain exacerbated by walking, standing or lifting * Symptoms are at least partially alleviated by lying down * Prolonged post-coital ache * Absence of non-venous origin CPP as determined by Gynecology examination 2. Symptoms-Varices-Pathophysiology Classification18 including of one of the following: •S2V2PBGV,R,NT, S2V2PRGV,R,NT , S2V2PLGV,R,NT, with or without S2V2 PBIIV,R,NT, S2V2 PLIIV,R,NT, S2V2 PRIIV,R,NT 3. CT, TAUS and diagnostic venography (if needed) imaging review for pelvic venous imaging factors * Left or right ovarian vein diameter greater than or equal to 6 mm as documented by TAUS or CT * Presence of intrabdominal/pelvic varices as documented by TAUS or CT (≥1 veins, \>5 mm diameter) * Presence of venous reflux in ovarian and/or inter