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Recruiting Phase 4 NCT04207931

NCT04207931 Treatment Results for Patients With Central Centrifugal Cicatricial Alopecia (CCCA): a Multicenter Prospective Study

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Clinical Trial Summary
NCT ID NCT04207931
Status Recruiting
Phase Phase 4
Sponsor Wake Forest University Health Sciences
Condition Central Centrifugal Cicatricial Alopecia (CCCA)
Study Type INTERVENTIONAL
Enrollment 250 participants
Start Date 2018-04-30
Primary Completion 2026-11

Trial Parameters

Condition Central Centrifugal Cicatricial Alopecia (CCCA)
Sponsor Wake Forest University Health Sciences
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 250
Sex FEMALE
Min Age 18 Years
Max Age 60 Years
Start Date 2018-04-30
Completion 2026-11
Interventions
Topical steroid class I-IITriamcinolone AcetonideDoxycyline

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Brief Summary

The objective of this study is to examine photos of CCCA patients taken before and after treatment to compare treatment outcomes between different treatment groups

Eligibility Criteria

Inclusion Criteria: * African-American women, ages 18-60 years old * with a clinical diagnosis and biopsy-proven CCCA, with Central Scalp Alopecia Scale severity 1 through 4 will be included in this study * These subjects will be seen and treated in Wake Forest Baptist Health Dermatology Outpatient Clinic Exclusion Criteria: * Patients with other forms of hair loss in addition to CCCA will be excluded * Other patients to be excluded are those with other forms of inflammatory scalp disease (with the exception of mild seborrheic dermatitis) * patients who have had topical treatment for CCCA within the past 4 months (including topical steroids, topical minoxidil, or any other topical hair regrowth medication) * patients who have been on a long-term oral antibiotics for hair loss within the past year * patients who have undergone more than two rounds of intralesional steroid injections to the scalp in the past one year.

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