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Recruiting NCT02851758

NCT02851758 Transplantation of Autologously Derived Mitochondria Following Ischemia

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Clinical Trial Summary
NCT ID NCT02851758
Status Recruiting
Phase
Sponsor Boston Children's Hospital
Condition Extracorporeal Membrane Oxygenation Complication
Study Type INTERVENTIONAL
Enrollment 16 participants
Start Date 2017-08-02
Primary Completion 2027-06

Eligibility & Interventions

Sex All sexes
Min Age N/A
Max Age 17 Years
Study Type INTERVENTIONAL
Interventions
autologous mitochondria transplantation

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 16 participants in total. It began in 2017-08-02 with a primary completion date of 2027-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring extracorporeal membrane oxygenation (ECMO), by direct injection of autogeneic mitochondria into the ischemic myocardium.

Eligibility Criteria

Inclusion Criteria: * Pediatric cardiology patients under the age of 18 on ECMO * concerns for ischemic injury on the Cardiac Intensive Care Unit Exclusion Criteria: * Known mitochondria disorders

Contact & Investigator

Central Contact

Breanna Piekarski, RN, BSN

✉ breanna.piekarski@cardio.chboston.org

📞 617-919-4457

Principal Investigator

Sitaram M Emani, MD

PRINCIPAL INVESTIGATOR

Boston Children's Hospital

Frequently Asked Questions

Who can join the NCT02851758 clinical trial?

This trial is open to participants of all sexes, up to 17 Years, studying Extracorporeal Membrane Oxygenation Complication. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT02851758 currently recruiting?

Yes, NCT02851758 is actively recruiting participants. Contact the research team at breanna.piekarski@cardio.chboston.org for enrollment information.

Where is the NCT02851758 trial being conducted?

This trial is being conducted at Boston, United States.

Who is sponsoring the NCT02851758 clinical trial?

NCT02851758 is sponsored by Boston Children's Hospital. The principal investigator is Sitaram M Emani, MD at Boston Children's Hospital. The trial plans to enroll 16 participants.

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