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Recruiting NCT05163197

NCT05163197 Transperineal Laser Ablation Treatment (TPLA) for Prostate Cancer (PCa) Registry

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Clinical Trial Summary
NCT ID NCT05163197
Status Recruiting
Phase
Sponsor Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Condition Prostate Cancer
Study Type OBSERVATIONAL
Enrollment 200 participants
Start Date 2021-10-01
Primary Completion 2026-10-01

Eligibility & Interventions

Sex Male only
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Transperineal Laser Ablation of Prostate Cancer

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 200 participants in total. It began in 2021-10-01 with a primary completion date of 2026-10-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Rationale: Transperineal laser ablation (TPLA) treatment for prostate cancer (PCa) is a minimal invasive focal therapy technique studied worldwide to determine its efficacy. In pilot studies it has shown to be a safe and feasible technique and it has potential to preserve continence and potency over current standard radical therapies. However, (long-term) treatment outcomes of TPLA for PCa remain largely unknown. The aim of this international retrospective registry is to collect and combine data on patients treated TPLA for PCa in order to provide data on safety, feasibility, functional and oncological outcomes. Objective: To assess safety and feasibility of TPLA for PCa, to assess functional and oncological outcomes of TPLA for PCa and to determine baseline patient characteristics in a multicentre cohort. Study design: This is an international, retrospective observational registry in which data is recorded of patients who have been treated with TPLA for PCa. Study population: Male patients treated with TPLA for PCa. Main study parameters/endpoints: The primary endpoint of this registry is oncological outcomes of TPLA for PCa. Secondary endpoints are safety, feasibility and functional outcomes of TPLA for PCa.

Eligibility Criteria

Inclusion Criteria: * Male, histological-confirmed disease of localized prostate cancer, TPLA treatment for PCa is performed Exclusion Criteria: * Age \< 18 years

Contact & Investigator

Central Contact

L. A. van Riel, MD

✉ l.a.vanriel@amsterdamumc.nl

📞 +31 6 50 06 30 94

Principal Investigator

J. R. Oddens, MD, PhD

PRINCIPAL INVESTIGATOR

Principal Investigator

Frequently Asked Questions

Who can join the NCT05163197 clinical trial?

This trial is open to male participants only, aged 18 Years or older, studying Prostate Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05163197 currently recruiting?

Yes, NCT05163197 is actively recruiting participants. Contact the research team at l.a.vanriel@amsterdamumc.nl for enrollment information.

Where is the NCT05163197 trial being conducted?

This trial is being conducted at Amsterdam, Netherlands.

Who is sponsoring the NCT05163197 clinical trial?

NCT05163197 is sponsored by Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA). The principal investigator is J. R. Oddens, MD, PhD at Principal Investigator. The trial plans to enroll 200 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology