To Study the Mortality Outcome of Controlled Blood Pressure Participants
Trial Parameters
Brief Summary
Despite advances in antihypertensive therapy, some patients with well-controlled blood pressure still experience fatal outcomes. This paradox raises critical questions about the efficacy of blood pressure-targeted interventions and whether BP control alone ensures survival. This systematic review and meta-analysis aims to evaluate all-cause mortality and cardiovascular death among hypertensive patients who achieved BP targets in RCTs or open-label trials. To determine whether achieving controlled blood pressure through intentional intervention (pharmacological or procedural) in RCTs or open-label studies reduces mortality (all-cause and cardiovascular) in hypertensive patients.
Eligibility Criteria
Inclusion Criteria: * Adults ≥18 years with diagnosed hypertension Blood pressure controlled at target values defined by the study (e.g., \<140/90 mmHg or \<130/80 mmHg) Any comorbidity allowed unless the study focuses on pregnancy or pediatric population Exclusion Criteria: * Observational or retrospective studies Pediatric or pregnant participants Case reports, editorials, or conference abstracts without full data Studies not reporting mortality outcomes separately for controlled BP