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Recruiting Phase 1 NCT07265466

to Evaluate the Safety and the Pharmacokinetic and Pharmacodynamic Interactions Between JP-1366 and Clopidogrel, Aspirin, Atorvastatin and Apixaban

Trial Parameters

Condition Drug Drug Interaction (DDI)
Sponsor Onconic Therapeutics Inc.
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 96
Sex ALL
Min Age 19 Years
Max Age 64 Years
Start Date 2025-11-17
Completion 2026-03-30
Interventions
JP-1366 and clopidogrelJP-1366 and aspirinJP-1366 and atorvastatin

Brief Summary

to Evaluate the Safety and the Pharmacokinetic and Pharmacodynamic Interactions between JP-1366 and Clopidogrel, Aspirin, Atorvastatin and Apixaban

Eligibility Criteria

Inclusion Criteria: * Healthy subject aged ≥ 19 years to \< 65 years at the time of screening * Subjects who weigh ≥ 50 kg (or ≥ 45 kg in the case of females) with body mass index (BMI) of ≥ 18.0 kg/m2 and ≤ 30.0 kg/m2 * Subjects who have voluntarily decided to participate after fully understanding the clinical trial based on the detailed explanation given, and have provided written informed consent before the screening procedure. Exclusion Criteria: * Subject who has a clinically significant history of disease in the liver, kidneys, digestive system, respiratory system, musculoskeletal system, endocrine system, neuropsychiatric system, hematopoietic and oncological system, or cardiovascular system. * The Subject who has a clinically significant bleeding or a history of congenital or acquired bleeding disorders such as hemophilia * Subject who has a history of gastrointestinal disorders (e.g., Crohn's disease, ulcerative disease, etc.) or surgery (excluding appendectomy, hernia repair,

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