NCT07048171 TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS
| NCT ID | NCT07048171 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Postgraduate Institute of Dental Sciences Rohtak |
| Condition | Apicomarginal Defects |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2025-04-18 |
| Primary Completion | 2026-04-18 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2025-04-18 with a primary completion date of 2026-04-18.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
To determine the effect of allograft and iPRF with or without collagen membrane on healing of apicomarginal defects : A Randomized Controlled Trial
Eligibility Criteria
Inclusion Criteria: 1. Patients with no general medical contraindications for oral surgical procedures (ASA-I and ASA-II according to the classification of the American Society of Anesthesiologist's). 2. Patients aged 18 years and above, presenting with chronic suppurative apical periodontitis in at least one tooth, 3. Radiographic evidence of apical radiolucency with periodontal pocket depth exceeding 6 mm confined to buccal aspect of the root. 4. Repeated abscess discharge despite satisfactory root canal treatment. 5.Patients with apicomarginal defects showing a denuded buccal bone plate 6.Failed primary root canal treatment 7.Adequate final restoration with no clinical evidence of coronal leakage. Exclusion Criteria: 1. Clinical or radiographic evidence of root fracture. 2. Resorptive processes involving more than apical third of the root. 3. Chronic generalized periodontitis. 4. Failed previous endodontic surgery or failed root canal re-treatment. 5. Any systemic disease contraindicating oral surgery including uncontrolled diabetes and pregnancy, any condition effecting rate of healing like smoking.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07048171 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Apicomarginal Defects. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07048171 currently recruiting?
Yes, NCT07048171 is actively recruiting participants. Contact the research team at tewarisanjayrohtak@yahoo.com for enrollment information.
Where is the NCT07048171 trial being conducted?
This trial is being conducted at Rohtak, India.
Who is sponsoring the NCT07048171 clinical trial?
NCT07048171 is sponsored by Postgraduate Institute of Dental Sciences Rohtak. The trial plans to enroll 50 participants.