NCT07094100 Tissue Engineered Cartilage to Repairing Articular Cartilage Defects
| NCT ID | NCT07094100 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The First Affiliated Hospital of Xinxiang Medical College |
| Condition | Cartilage Injury |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2026-04-20 |
| Primary Completion | 2027-12 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2026-04-20 with a primary completion date of 2027-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The joint cartilage constructed by combining bone marrow mesenchymal stem cells with three-dimensional materials has achieved the goal of repairing joint cartilage.
Eligibility Criteria
Inclusion Criteria: 1. The patients' age ranges from 18 to 65 years old, and gender is not restricted; 2. The imaging results show that the epiphyseal growth is mature; 3. The defects or localized injuries of joint cartilage caused by trauma or other reasons; 4. The injured area is the distal weight-bearing surface of the femoral condyle of the knee joint, with no more than 4 lesions, and there is no injury to the cruciate ligaments; 5. The patients voluntarily sign and provide a written informed consent form and are willing to closely cooperate with the doctor's strict postoperative rehabilitation program. Exclusion Criteria: 1. The patient is extremely overweight, with a body mass index greater than 35; 2. The lower limb alignment is valgus by more than 10° and varus by more than 5°; 3. Multiple ligament injuries; 4. There are numerous bad habits such as heavy smoking, drug abuse, and excessive alcohol consumption; 5. Has undergone open knee joint surgery within the past six months; 6. Has severe joint stiffness or fibrosis; 7. Has an allergic constitution or a history of allergic reactions to collagen; 8. Has mental abnormalities; 9. Cannot or is unwilling to undergo rehabilitation training; 10. Has primary cardiovascular diseases, lung diseases, endocrine and metabolic disorders, or other serious diseases that affect their daily life, such as tumors or AIDS; 11. Pregnant or lactating women, or those planning to conceive during the trial period; 12. Other acute or chronic diseases, for which the researchers consider surgery to be inappropriate.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07094100 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Cartilage Injury. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07094100 currently recruiting?
Yes, NCT07094100 is actively recruiting participants. Contact the research team at 13937354075@163.com for enrollment information.
Where is the NCT07094100 trial being conducted?
This trial is being conducted at Xinxiang, China.
Who is sponsoring the NCT07094100 clinical trial?
NCT07094100 is sponsored by The First Affiliated Hospital of Xinxiang Medical College. The trial plans to enroll 30 participants.