NCT06717542 Tissue Analysis of Liver Grafts as a Predictor of Transplant Outcome.
| NCT ID | NCT06717542 |
| Status | Recruiting |
| Phase | — |
| Sponsor | IRCCS Azienda Ospedaliero-Universitaria di Bologna |
| Condition | Hepatic Transplantation |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2023-01-17 |
| Primary Completion | 2027-07 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2023-01-17 with a primary completion date of 2027-07.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Despite the good clinical results in terms of outcome with the application of HOPE prior to liver transplantation, very little is still known about the phenotypic and molecular changes that occur during perfusion/preservation during HOPE, particularly with regard to endothelial trophism and activation. Delving into these aspects would be very useful to allow personalised perfusion treatments in the future, thus improving the outcome of transplantation.
Eligibility Criteria
Inclusion Criteria: * For Donors: Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis. * HOPE performed on the liver graft prior to transplantation. * For Recipients: * Availability of enough tissue for histological, immunohistochemical and RT-PCR analysis. * Age greater than/equal to 18 years. Exclusion Criteria: * None
Contact & Investigator
Francesco Vasuri, MD
PRINCIPAL INVESTIGATOR
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Frequently Asked Questions
Who can join the NCT06717542 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Hepatic Transplantation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06717542 currently recruiting?
Yes, NCT06717542 is actively recruiting participants. Contact the research team at francesco.vasuri2@unibo.it for enrollment information.
Where is the NCT06717542 trial being conducted?
This trial is being conducted at Bologna, Italy.
Who is sponsoring the NCT06717542 clinical trial?
NCT06717542 is sponsored by IRCCS Azienda Ospedaliero-Universitaria di Bologna. The principal investigator is Francesco Vasuri, MD at IRCCS Azienda Ospedaliero-Universitaria di Bologna. The trial plans to enroll 200 participants.