This study investigates whether eating during a restricted time window each day can help with weight management and improve muscle health and metabolism. Researchers are testing this approach as a potential long-term strategy for preventing and treating obesity.
Key Objective: This trial tests whether time-restricted eating can help people lose weight while preserving muscle mass and improving metabolic health.
Who to Consider: People who are overweight and interested in trying a time-restricted eating approach to improve their health may want to consider participating in this study.
Trial Parameters
Brief Summary
Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.
Eligibility Criteria
Inclusion Criteria: * Resides in Northwest Arkansas * Age 25-50 years * BMI \> 25 * All ethnicities * Female and male Exclusion Criteria: * Food allergies * Pregnant or breastfeeding * Dietary restrictions (e.g. vegetarian, vegan, etc.) * Trying to lose weight in last 3 months * Pre-existing health conditions related to obesity (e.g. cardiovascular disease, diabetes, hypertension) * Prescription medications related to heart disease or type 2 diabetes * Fear of needles * Smoker or vaping * Currently taking protein supplements or other nutritional supplements which may interfere with study outcomes * Consumes \>4 alcoholic beverages per week