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Recruiting Phase 4 NCT05023369

This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time

Trial Parameters

Condition Femoral Neck Fractures
Sponsor Ente Ospedaliero Cantonale, Bellinzona
Study Type INTERVENTIONAL
Phase Phase 4
Enrollment 110
Sex ALL
Min Age 50 Years
Max Age 90 Years
Start Date 2021-12-10
Completion 2026-11-01
Interventions
Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)

Brief Summary

The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of hospitalisation, use of analgesics drugs.

Eligibility Criteria

Inclusion Criteria: * Patients undergoing unilateral cemented hip endoprosthesis for femoral neck fracture * Patients aged 50-90 years old * Patients with a BMI \>18.5 and \<35 * Patients able to provide informed consent and follow all the study procedures as indicated by the protocol * Informed Consent as documented by signature Exclusion Criteria: * Contraindications to steroids * Revision endoprosthesis * Active steroid or immunosuppressive therapy in the last 30 days before the operation * Pregnant or breast-feeding women * Presence of other clinically significant concomitant disease states (ASA IV) * Uncontrolled diabetes mellitus * Contraindications to NSAIDs * Chronic systemic diseases as immunodeficiency, autoimmune disease (Systemic Lupus Erythematosus, SLE), gout, rheumatic arthritis * Known or suspected non-compliance, drug or alcohol abuse * Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the partici

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