NCT07197424 The Use of Robot Assisted Magnetically Controlled Capsule Endoscopy in Patients With Iron Deficiency Anaemia
| NCT ID | NCT07197424 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Edinburgh |
| Condition | Iron Deficiency Anaemia |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-05-11 |
| Primary Completion | 2027-03 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2026-05-11 with a primary completion date of 2027-03.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In this study the investigators will recruit patients who have already had an upper gastrointestinal (GI) tract endoscopy (OGD) and lower GI tract investigations which did not identify the source of iron deficiency anaemia, and who need the small bowel to be investigated. This will comprise both patients who would have proceeded directly to small bowel capsule endoscopy (SBCE) under standard care and also those from whom an initial 'watch and wait' approach may have been adopted before proceeding to SBCE. The investigators propose to investigate these patients during a single patient visit to Leith Community Treatment Centre, Edinburgh, Scotland, with a CE marked robotic capsule system which can examine both the upper GI tract (i.e. the oesophagus and the stomach) and the small bowel in one investigation using a magnetic guided capsule. The aim of the study is to compare the findings from OGD with the robotic capsule system and to determine if such a system may safely replace OGD - thus examining the upper GI tract and small bowel for IDA in one less invasive investigation. This has the potential to decrease patient discomfort, stress and anxiety, while also reducing pressure on busy endoscopy departments, helping to ensure that the right patients receive the right investigations in a timely manner.
Eligibility Criteria
Inclusion Criteria: * Adult patients aged 18 and above * Confirmed diagnosis of iron deficiency anaemia (either recent onset or recurrent) * No significant cause for iron deficiency anaemia previously identified on upper GI endoscopy, colonoscopy or CT colonography * Patients who would either have proceeded directly to small bowel capsule endoscopy (SBCE) or who would have had an initial 'watch and wait' period prior to undergoing SBCE Exclusion Criteria: * Known or suspected gastrointestinal obstruction, strictures or fistulae * Previous abdominal surgery * Dysphagia * Patients with a pacemaker, defibrillator or other implanted electronic device * In vivo retention with medical metal fittings - shunts, plates, stents or clips * A history of metal fragments in the eyes or elsewhere in the body * Confirmed or possible pregnancy * Patients who are not deemed to have capacity according to the Adults with Incapacity Act * Patients who are currently part of another research study
Contact & Investigator
John N Plevris, MD, DM, PhD(E), FRCPE, FEBGH
PRINCIPAL INVESTIGATOR
University of Edinburgh
Frequently Asked Questions
Who can join the NCT07197424 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Iron Deficiency Anaemia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07197424 currently recruiting?
Yes, NCT07197424 is actively recruiting participants. Contact the research team at j.plevris@ed.ac.uk for enrollment information.
Where is the NCT07197424 trial being conducted?
This trial is being conducted at Edinburgh, United Kingdom.
Who is sponsoring the NCT07197424 clinical trial?
NCT07197424 is sponsored by University of Edinburgh. The principal investigator is John N Plevris, MD, DM, PhD(E), FRCPE, FEBGH at University of Edinburgh. The trial plans to enroll 100 participants.