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Recruiting Phase 2 NCT06622759

The Use of a Porcine Collagen Matrix for the Prevention of Buccal Bone Wall Resorption During Implant Placement in the Aesthetic Zone.

Trial Parameters

Condition Soft Tissue Augmentation
Sponsor Aristotle University Of Thessaloniki
Study Type INTERVENTIONAL
Phase Phase 2
Enrollment 36
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2023-03-24
Completion 2025-08-20
Interventions
CTGCollagen MatrixControl group

Brief Summary

Aim: To provide a comparative assessment of the clinical and radiographic effect of porcine collagen matrix when placed buccally at the time of single implant placement in the aesthetic zone vs autogenous connective tissue graft in terms of buccal bone resorption and soft tissue augmentation 6 months post operative. Histological assessment and patient reported outcomes were reported

Eligibility Criteria

Inclusion Criteria: 1. Generally healthy adult patients. 2. 18 years or older. 3. Need for replacement of single implant in the upper aesthetic zone (second premolar to second premolar) 4. Ridge width (bucco-lingual) no greater than 6 mm at its narrowest point. 5. Minimum 2mm of attached gingiva. 6. Ability to comply with the study related procedures such as exercising good oral hygiene and attending all follow-up examinations. 7. Ability to fully understand the nature of the proposed surgery and ability to sign the informed consent form Exclusion Criteria: 1. Poor oral hygiene (FMPS \< 20%, FMBS \< 15%) and poor motivation 2. Heavy smokers (\>10 cigarettes per day) 3. Need for bone augmentation 4. Untreated periodontitis 5. General contraindications for dental and/or surgical treatment 6. History of malignancy, radiotherapy, or chemotherapy for malignancy within the past 5 years 7. Women of child bearing age, not using a standard accepted method for contraception 8. Pregnancy or breas

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