NCT07511673 The Study Tests if Preoperative Dental Screening is Superior to no Preoperative Dental Screening in Improving the Outcome of Patients Undergoing Surgical Cardiac Valve Replacement or Transcatheter Cardiac Valve Implantation.
| NCT ID | NCT07511673 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Region Skane |
| Condition | Infective Endocarditis (IE) |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,300 participants |
| Start Date | 2026-05-06 |
| Primary Completion | 2030-12-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,300 participants in total. It began in 2026-05-06 with a primary completion date of 2030-12-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This randomized, multicenter, open-label trial evaluates whether preoperative dental screening improves outcomes in patients undergoing surgical or transcatheter cardiac valve intervention. Participants are randomized 1:1 to preoperative dental screening or no screening. The primary outcome is time to first occurrence of all-cause death, redo-intervention of the index valve, or definite infective endocarditis within 2 years. The study uses registry-based follow-up to ensure complete outcome ascertainment.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Accepted for cardiac valve intervention * Able to provide informed consent Exclusion Criteria: * Previous or ongoing infective endocarditis * Urgent surgery * Pain from loose tooth/teeth * Immunosuppressive therapy (excluding corticosteroids) * Inability to provide informed consent * Expected loss to follow-up
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07511673 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Infective Endocarditis (IE). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07511673 currently recruiting?
Yes, NCT07511673 is actively recruiting participants. Contact the research team at patrik.gilje@skane.se for enrollment information.
Where is the NCT07511673 trial being conducted?
This trial is being conducted at Gothenburg, Sweden, Linköping, Sweden, Lund, Sweden, Örebro, Sweden and 1 additional location.
Who is sponsoring the NCT07511673 clinical trial?
NCT07511673 is sponsored by Region Skane. The trial plans to enroll 1,300 participants.