← Back to Clinical Trials
Recruiting Phase 2, Phase 3 NCT07459790

The Study is Being Conducted to Find a New Treatment for Patients Suffering From Interstitial Cystitis With Hunner's Lesions

Trial Parameters

Condition IC
Sponsor JSC NextGen
Study Type INTERVENTIONAL
Phase Phase 2, Phase 3
Enrollment 180
Sex FEMALE
Min Age 18 Years
Max Age 65 Years
Start Date 2023-12-29
Completion 2027-10-30
Interventions
Neovasculgen®Placebo

Brief Summary

To evaluate the efficacy and safety of Neovasculgen in interstitial cystitis with Hunner's lesions to reduce cicatricial changes in the bladder caused by electrocoagulation and to prevent secondary bladder shrinkage with a decrease in its volume.

Eligibility Criteria

Inclusion Criteria: 1. Written informed consent prior to any study-related procedures. 2. Women aged 18 to 65 years, inclusive. 3. A confirmed diagnosis of painful bladder syndrome/interstitial cystitis, characterized by pelvic pain associated with filling or emptying the bladder, frequent urination day and night, with symptoms lasting at least 12 months, with the exclusion of a urinary tract infection or other disease that could cause such symptoms. 4. The presence of Hunner's lesions of the bladder during cystoscopy with hydrobougienage of the bladder (2 minutes, 80 cm H2O). 5. A glycated hemoglobin level within the normal range for the patient's age group. 6. Ability to comply with all study requirements, in the opinion of the investigator, including regularly keeping a voiding diary, completing questionnaires, and attending all scheduled study visits. 7. Women who are of childbearing potential must have negative pregnancy test results and must use reliable contraception throughout

Related Trials