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Recruiting NCT06219486

The Safe Fast Track Study

Trial Parameters

Condition Emergency Department
Sponsor Odense University Hospital
Study Type INTERVENTIONAL
Phase N/A
Enrollment 1,538
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-01-22
Completion 2025-07-01
Interventions
D-dimer

Brief Summary

Emergency departments (ED) internationally are treating an increasing number of patients. Most require hospital services but some could be better cared for on alternative pathways. D-dimer has some unique properties. It is non-specific and is elevated in many acute condi- tions; but conversely remains normal in the absence of significant disease. Previous studies have shown that having a normal D-dimer on arrival to the emergency department is associated with a very low risk of 30-day all-cause mortality. The investigators propose a multicenter randomized controlled trial using D-dimer to identify patients at low risk and test if providing this information will change time to discharge disposition by the treating physician.

Eligibility Criteria

Inclusion Criteria: * Age 18 or above * Able to provide oral and written informed consent in Danish * Blood tests ordered on arrival as part of standard of care * Ambulatory on arrival or walking to the ambulance (i.e., stable independent gait) * Normal vital signs (i.e., National Early Warning Score \< 3) Exclusion Criteria: * Unstable condition requiring immediate care in the resuscitation area * Triage level red (i.e., the most urgent patients) * Trauma (minor and major) patients * High likelihood of requiring a D-dimer analysis on clinical indications during the current hospital contact (e.g., suspected venous thromboembolic disease) that will be ordered on arrival regardless of this study * Previous participation in the study

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