NCT04861818 The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults
| NCT ID | NCT04861818 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of North Carolina, Greensboro |
| Condition | Aerobic Exercise |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2021-06-21 |
| Primary Completion | 2025-12-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2021-06-21 with a primary completion date of 2025-12-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Cumulative evidence indicates that a single bout of exercise has beneficial impacts on memory in young adults. From a physiological perspective, acute exercise leads to changes of heart rate variability (HRV), which is associated with memory retrieval process. From a psychological perspective, acute exercise increases the arousal level and thus facilitates cognitive processing including memory storage and retrieval. Such HRV- and/or arousal-based effects of exercise on memory could be differed by the time of day in young adults based on their circadian rhythms of HRV. Moreover, young adults prefer afternoon or evening to morning in their circadian rhythms, demonstrating less wakefulness and lower memory performance in the morning relative to afternoon. Based on the potential psychophysiological mechanisms, exercise could impact young adults' memory differently by the time of day. The investigators aim to 1) determine the extent to which the time of day modulates how moderate-intensity cardiovascular exercise impacts verbal-auditory and visuospatial short- and long-term memory in young adults, and 2) consider potential psychological and physiological markers that may mediate exercise's effects on cognitive performance. As cognitive benefits of exercise might differ by the time of day, it is important to investigate such interaction and make the right recommendations of the timing of exercise for young adults in academic settings.
Eligibility Criteria
Inclusion Criteria: * Between the ages of 18-25. * Currently meeting the American College of Sports Medicine's recommended guidelines of activity (at least 90 min/week of moderate and/or vigorous physical activity). * Willing to participate for 4 days (2 visits) and refrain from exercise outside of the lab for 4 days (1 day before and the day of two visits). Exclusion Criteria: * Any known history of cardiac, pulmonary, or metabolic disease (e.g. cardiovascular disease, asthma, diabetes). * A current musculoskeletal injury, mental illness (e.g., depression, anxiety, or stress disorders), or sleep disorder.
Contact & Investigator
Kyoung Shin Park, PhD
PRINCIPAL INVESTIGATOR
UNC Greensboro
Frequently Asked Questions
Who can join the NCT04861818 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 25 Years, studying Aerobic Exercise. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04861818 currently recruiting?
Yes, NCT04861818 is actively recruiting participants. Contact the research team at k_park4@uncg.edu for enrollment information.
Where is the NCT04861818 trial being conducted?
This trial is being conducted at Greensboro, United States.
Who is sponsoring the NCT04861818 clinical trial?
NCT04861818 is sponsored by University of North Carolina, Greensboro. The principal investigator is Kyoung Shin Park, PhD at UNC Greensboro. The trial plans to enroll 80 participants.