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Recruiting NCT06330012

NCT06330012 The Resistance Mechanism of Trastuzumab Deruxtexan in HER2 Positive Breast Cancer Patients.

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Clinical Trial Summary
NCT ID NCT06330012
Status Recruiting
Phase
Sponsor Samsung Medical Center
Condition HER2-positive Breast Cancer
Study Type INTERVENTIONAL
Enrollment 50 participants
Start Date 2024-03-18
Primary Completion 2025-01-15

Eligibility & Interventions

Sex Female only
Min Age N/A
Max Age N/A
Study Type INTERVENTIONAL
Interventions
GeoMx data analysis with clinical outcome

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 50 participants in total. It began in 2024-03-18 with a primary completion date of 2025-01-15.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This study is the spatial transcriptomic approach for revealing the resistance mechanism of trastuzumab deruxtexan in HER2 positive breast cancer patients.

Eligibility Criteria

Inclusion Criteria: * HER2 positive breast cancer * Stage IV disease * Treated with T-Dxd * Available FFPE samples Exclusion Criteria: * TNBC breast cancer * Hormone receptor positive breast cancer * Non-available FFPE samples * Treated except T-Dxd

Contact & Investigator

Central Contact

Ji-Yeon Kim

✉ jyeon25@skku.edu

📞 82-2-3410-3459

Frequently Asked Questions

Who can join the NCT06330012 clinical trial?

This trial is open to female participants only, studying HER2-positive Breast Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06330012 currently recruiting?

Yes, NCT06330012 is actively recruiting participants. Contact the research team at jyeon25@skku.edu for enrollment information.

Where is the NCT06330012 trial being conducted?

This trial is being conducted at Seoul, South Korea.

Who is sponsoring the NCT06330012 clinical trial?

NCT06330012 is sponsored by Samsung Medical Center. The trial plans to enroll 50 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology