NCT06653946 the Predictors of Hemorrhagic Transformation Subtypes in Acute Embolic Stroke Patients
| NCT ID | NCT06653946 |
| Status | Recruiting |
| Phase | Phase 4 |
| Sponsor | Kafrelsheikh University |
| Condition | Ischemic Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 716 participants |
| Start Date | 2022-07-01 |
| Primary Completion | 2024-07-01 |
Trial Parameters
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Brief Summary
The investigators evaluated the impact of AF on different subtypes of post-alteplase hemorrhagic transformation of brain infarction.
Eligibility Criteria
Inclusion Criteria: * The investigators enrolled individuals of both genders, aged between 18 and 75, * All patients had acute first-ever embolic ischemic stroke and were eligible for thrombolysis. * All patients had Atrial fibrillation Exclusion Criteria: * The investigators excluded patients who had alteplase contraindications * The investigators excluded patients who did not receive the total dose of alteplase for any reason. * The investigators excluded patients who had a known history of persistent or recurrent CNS pathology (e.g., epilepsy, meningioma, multiple sclerosis) * The investigators excluded patients who had recurrent ischemic stroke diagnosed by appropriate clinical history and/or MRI brain findings. * The investigators excluded patients with symptoms of major organ failure, active malignancies, or an acute myocardial infarction within the previous six weeks. * The investigators also excluded pregnant and lactating patients with stroke due to venous thrombosis and strok
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