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Recruiting NCT04365855

NCT04365855 The Olmsted NAFLD Epidemiology Study (TONES)

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Clinical Trial Summary
NCT ID NCT04365855
Status Recruiting
Phase
Sponsor Mayo Clinic
Condition Non-Alcoholic Fatty Liver Disease
Study Type INTERVENTIONAL
Enrollment 800 participants
Start Date 2020-10-10
Primary Completion 2028-06

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
Magnetic Resonance ElastographyBlood drawLiver biopsy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 800 participants in total. It began in 2020-10-10 with a primary completion date of 2028-06.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.

Eligibility Criteria

Inclusion Criteria: * Olmsted County residents at the time of search * Age 18 or older * No personal history of NAFLD diagnosis (administrative codes) Exclusion Criteria: * Alcohol in excess (more than 20 gm per week in women and 30 gm per week in men) * Currently pregnant * Have contraindications to MRI (MRI incompatible implanted devices, severe claustrophobia)

Contact & Investigator

Central Contact

Jodie A Cogswell

✉ cogswell.jodie@mayo.edu

📞 507-266-3995

Principal Investigator

ALINA M ALLEN, MD

PRINCIPAL INVESTIGATOR

Mayo Clinic

Frequently Asked Questions

Who can join the NCT04365855 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Non-Alcoholic Fatty Liver Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04365855 currently recruiting?

Yes, NCT04365855 is actively recruiting participants. Contact the research team at cogswell.jodie@mayo.edu for enrollment information.

Where is the NCT04365855 trial being conducted?

This trial is being conducted at Rochester, United States.

Who is sponsoring the NCT04365855 clinical trial?

NCT04365855 is sponsored by Mayo Clinic. The principal investigator is ALINA M ALLEN, MD at Mayo Clinic. The trial plans to enroll 800 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology