NCT07059234 The Motor Activity - Subjective Energy (MASE) Project
| NCT ID | NCT07059234 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Bern |
| Condition | Depressive Disorder, Major |
| Study Type | INTERVENTIONAL |
| Enrollment | 180 participants |
| Start Date | 2025-09-02 |
| Primary Completion | 2027-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 180 participants in total. It began in 2025-09-02 with a primary completion date of 2027-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This approach utilizes accelerometry to measure NEA and electronic diaries for real-time psychological assessments, overcoming limitations of traditional methods such as retrospective bias and low ecological validity. Brief episodes of physical activity in daily life, which are distinctly different from structured exercise sessions, are generally linked to improved affective well-being. Notably, feelings of energy are particularly associated with incidental, unstructured, and non-exercise activities. Clinically, psychomotor retardation and diminished mood are key diagnostic features of MDD, with evidence suggesting that lower motor activity differentiates MDD patients from controls and that increased activity correlates with treatment response. In this context, the MASE project aims to design personalized BA interventions that focus on increasing NEA and, in turn, enhancing subjective energy levels to reduce depressive symptoms and prevent relapse.
Eligibility Criteria
Inclusion Criteria: * Sufficient knowledge of the German language * Written informed consent. * Score \> 15 on the Montgomery Asberg Depression rating scale (MADRS) for MDD group. * Remission within the past year and exhibit a MADRS score \< 10 for at least one month for rMDD group Exclusion Criteria: * Pregnancy at baseline * Claustrophobia * Pacemaker * Artificial heart valves * Active implants * Other psychiatric disorders * Acute suicidality, change of medication / psychotherapy during the intervention (not dosage but substance). * For healthy participants: history of any mental health condition or first-degree relative with affective / psychotic disorder
Contact & Investigator
Markus Reichert, Prof
STUDY DIRECTOR
Department of Sport and Exercise Science University of Salzburg
Frequently Asked Questions
Who can join the NCT07059234 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Depressive Disorder, Major. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07059234 currently recruiting?
Yes, NCT07059234 is actively recruiting participants. Contact the research team at claudio.nigg@unibe.ch for enrollment information.
Where is the NCT07059234 trial being conducted?
This trial is being conducted at Bern, Switzerland.
Who is sponsoring the NCT07059234 clinical trial?
NCT07059234 is sponsored by University of Bern. The principal investigator is Markus Reichert, Prof at Department of Sport and Exercise Science University of Salzburg. The trial plans to enroll 180 participants.