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depressive disorder major

Total Trials
6
Recruiting Now
6
Trial Phases
Phase 4, Phase 3, Phase 2

ClinicalMetric tracks all active clinical trials for depressive disorder major sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — depressive disorder major Clinical Trials

How many clinical trials are currently recruiting for depressive disorder major?
ClinicalMetric currently tracks 6 actively recruiting clinical trials for depressive disorder major, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 6. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for depressive disorder major?
depressive disorder major research spans Phase 2 (1 trial), Phase 3 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a depressive disorder major clinical trial?
Eligibility criteria for depressive disorder major trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
1
Phase 3
1
Phase 4
1
Top Sponsors
Janssen Research & Development, LLC 2 trials
Region Örebro County 1 trial
University of Campania Luigi Vanvitelli 1 trial
University of Bern 1 trial
University of Washington 1 trial

Recruiting Clinical Trials

NCT04057378 Phase 4
Recruiting

Optimal Electrical Stimulus During Electroconvulsive Therapy

Enrollment
800 pts
Location
Sweden
Sponsor
Region Örebro County
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NCT05988333
Recruiting

Psychoeducational Intervention for Families With a Member Affected by Major Depression

Enrollment
384 pts
Location
Italy
Sponsor
University of Campania Luigi V...
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NCT06559306 Phase 3
Recruiting

Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms

Enrollment
752 pts
Location
United States, Argen...
Sponsor
Janssen Research & Development...
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NCT07059234
Recruiting

The Motor Activity - Subjective Energy (MASE) Project

Enrollment
180 pts
Location
Switzerland
Sponsor
University of Bern
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NCT06005194
Recruiting

InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI

Enrollment
80 pts
Location
United States
Sponsor
University of Washington
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NCT06785012 Phase 2
Recruiting

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

Enrollment
100 pts
Location
United States
Sponsor
Janssen Research & Development...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology