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Recruiting NCT06438094

The Influence of Non-Carious Cervical Lesions on Root Coverage

Trial Parameters

Condition Gingival Recession
Sponsor Gonzalo Blasi
Study Type INTERVENTIONAL
Phase N/A
Enrollment 56
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2024-05-26
Completion 2026-05-25
Interventions
Root coverage surgery by means of a coronally advanced flap combined with a connective tissue graftReconstruction of the CEJ with a composite restoration followed by root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft

Brief Summary

The goal of this prospective cohort study is to evaluate the effect of non-carious cervical lesions (NCCLs) on the outcome of root coverage therapy. The main question it aims to answer is: In gingival recessions associated with NCCLs, characterized by an undetectable cemento-enamel junction (CEJ), reconstruction of the CEJ with a cervical composite restoration, prior to root coverage surgery by means of a coronally advanced flap combined with a connective tissue graft (CAF+CTG), provides similar clinical and patient-reported outcomes, as compared to the treatment of gingival recessions associated with NCCLs, characterized by a visible CEJ, with root coverage surgery only, by means of a CAF+CTG. In NCCLs where the CEJ is undetectable (B-type defect), the CEJ will be reconstructed before surgery with a cervical composite restoration mimicking the anatomic features of the contralateral, homologous tooth. CAF+CTG treatment will be performed in all cases. Participants will be assessed at 6 weeks, 3 months, and 6 months to evaluate clinical, volumetric, and patient-centred outcomes.

Eligibility Criteria

Inclusion Criteria: * Systemically healthy individuals older than 18 years old; * Healthy periodontal status according to the AAP/EFP definition; * Full-mouth plaque (FMPS) and bleeding scores (FMBS) ≤ 20%; * At least one facial RT1 GR in single-rooted teeth with a minimum depth of 2 mm, associated with a NCCL; * No history of periodontal surgery at the experimental site(s). Exclusion Criteria: * Pregnancy or lactation; * Self-reported smoking ≥10 cigarettes/day; * Metabolic diseases that negatively affect soft tissue healing (i.e., diabetes mellitus); * Any medication that may interfere with wound healing; * Prosthetic crown at experimental teeth; * Ongoing orthodontic therapy.

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