NCT07550907 The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors
| NCT ID | NCT07550907 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Zhongshan Ophthalmic Center, Sun Yat-sen University |
| Condition | Age-related Cataract |
| Study Type | OBSERVATIONAL |
| Enrollment | 300 participants |
| Start Date | 2026-04-20 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 300 participants in total. It began in 2026-04-20 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to evaluate the location of phacoemulsification tip measured by intraoperative OCT during cataract surgeries and its impact on early postoperative changes of cornea and visual acuity. The main question it aims to answer is: In patients with age-related cataracts undergoing phacoemulsification, does the location (supracapsular, iris-lens diaphragm, or endocapsular) of the phaco tip affect postoperative corneal changes and visual acuity at early postoperative stage? Eyes having phacoemulsification for cataracts will receive intraoperative OCT imaging to evaluate the location of the phaco tip during surgery, and corneal changes and visual acuity will be measured postoperatively.
Eligibility Criteria
Inclusion Criteria: * Age ≥ 50 years and ≤ 90 years * Diagnosis of unilateral/bilateral age-related cataract * Nuclear grade ≥2 in LOCSIII classification * Scheduled for cataract phacoemulsification combined with intraocular lens implantation * Pupil size ≥6mm after dilation * Corneal endothelial cell count ≥1500 cells/mm² Exclusion Criteria: * Diagnosis of severe systemic disease (e.g., severe hypertension or Alzheimer's disease) * History of ocular trauma or surgery * Presence of other ocular diseases (such as glaucoma, diabetic retinopathy, or high myopia) * Other ocular factors that may complicate the surgery (such as small pupil, shallow anterior chamber)
Frequently Asked Questions
Who can join the NCT07550907 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 90 Years, studying Age-related Cataract. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07550907 currently recruiting?
Yes, NCT07550907 is actively recruiting participants. Visit ClinicalTrials.gov or contact Zhongshan Ophthalmic Center, Sun Yat-sen University to inquire about joining.
Where is the NCT07550907 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT07550907 clinical trial?
NCT07550907 is sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University. The trial plans to enroll 300 participants.