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Recruiting NCT06425874

The Impact of Socioeconomic Determinants on the Patient Reported Outcomes in Young Breast Cancer Patients After Breast Surgery

Trial Parameters

Condition Breast Cancer
Sponsor Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,000
Sex FEMALE
Min Age 18 Years
Max Age 50 Years
Start Date 2024-02-29
Completion 2035-12-01
Interventions
Breast-conserving surgeryMastectomyMastectomy with reconstruction

Brief Summary

Breast-conserving surgery is the standard treatment for young breast cancer patients, while mastectomy with breast reconstruction is an alternative for those who are not eligible for Breast-conserving surgery. Several studies have compared the quality of life and patient satisfaction among individuals receiving different types of surgery (Breast-conserving surgery, mastectomy alone, or mastectomy with reconstruction). For example, Meghan R. demonstrated that patients undergoing Breast-conserving surgery experience a higher quality of life compared to those undergoing mastectomy with breast reconstruction, whereas J. Dauplat's study showed that patients who undergo mastectomy with breast reconstruction report a higher quality of life than those who undergo mastectomy alone. However, the investigators hypothesize that the advantages of a specific type of surgery over another, such as Breast-conserving surgery versus breast reconstruction, may vary among patients with different socioeconomic factors. For instance, the benefits of breast reconstruction over Breast-conserving surgery might be more pronounced in young patients who require a more socially active lifestyle. Additionally, the benefits of one type of surgery over another may also vary at different time points during post-operative follow-up. Furthermore, it is worth noting that most current studies have been conducted in Caucasian populations. In contrast to Caucasians, Asians typically have smaller breast volumes, potentially leading to more significant defects after Breast-conserving surgery and possibly poorer aesthetic outcomes. Therefore, a study focusing on Asian young breast cancer populations is necessary.

Eligibility Criteria

Inclusion Criteria: * Age between 18 and 50 years old. * The surgery time and procedure have been confirmed, and the surgical informed consent and research informed consent forms have been signed. * Informed consent obtained from patient. * Unilateral Breast Cancer. * Good health,the patient is able to tolerate general anesthesia and surgery, with an ECOG performance status of ≤2 points. * No history of breast/axillary radiation therapy. * Willing and capable of complying with the study protocol visits, treatment plans, and other research procedures. Exclusion Criteria: * Bilateral breast cancer. * Inflammatory breast cancer. * Stage IV breast cancer. * Physical examination and imaging suggest tumor infiltration into the skin, pectoralis major muscle, and other adjacent tissues. * Patients unable to tolerate surgery due to coagulation abnormalities. * In patients without evidence of breast cancer in the contralateral breast, requesting contralateral prophylactic mastectomy. * In patien

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