NCT06750939 The Impact of Propofol and Ketamine on Cardiovascular Collapse During Induction for Intubation
| NCT ID | NCT06750939 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kocaeli City Hospital |
| Condition | Cardiovascular Collapse |
| Study Type | OBSERVATIONAL |
| Enrollment | 128 participants |
| Start Date | 2024-07-15 |
| Primary Completion | 2025-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 128 participants in total. It began in 2024-07-15 with a primary completion date of 2025-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This prospective observational study evaluates the impact of propofol and ketamine on the risk of cardiovascular collapse during induction for endotracheal intubation in critically ill patients. Induction agents play a crucial role in managing hemodynamic stability, particularly in this vulnerable population. Propofol, known for its vasodilatory and myocardial depressant effects, has been associated with significant hypotension during induction. Conversely, ketamine, with its sympathomimetic properties, is often considered a safer alternative for hemodynamic stability. In addition to comparing the incidence of cardiovascular collapse-defined as severe hypotension or cardiac arrest-this study examines the relationship between these induction agents and shock indices, including systolic shock index, diastolic shock index, age-adjusted shock index, and modified shock index. These parameters will provide a more detailed understanding of the hemodynamic effects of each agent and their clinical implications. The findings aim to guide induction agent selection to optimize outcomes in critically ill patients.
Eligibility Criteria
Inclusion Criteria: * Patients aged over 18 years * Patients admitted to the intensive care unit (ICU) who undergo endotracheal intubation during their ICU stay will be included. Exclusion Criteria: * Patients who did not provide consent to participate in the study * Patients intubated due to cardiac arrest * Patients intubated outside the intensive care unit
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06750939 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Cardiovascular Collapse. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06750939 currently recruiting?
Yes, NCT06750939 is actively recruiting participants. Contact the research team at omermgin@yahoo.com for enrollment information.
Where is the NCT06750939 trial being conducted?
This trial is being conducted at Köseköy, Turkey (Türkiye).
Who is sponsoring the NCT06750939 clinical trial?
NCT06750939 is sponsored by Kocaeli City Hospital. The trial plans to enroll 128 participants.