← Back to Clinical Trials
Recruiting Phase 3 NCT07381803

The Impact of Fexofenadine Hydrochloride on the Prognosis of Patients Post-Acute Myocardial Infarction

Trial Parameters

Condition Zhejiang University
Sponsor Second Affiliated Hospital, School of Medicine, Zhejiang University
Study Type INTERVENTIONAL
Phase Phase 3
Enrollment 2,804
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-01-27
Completion 2026-12
Interventions
Fexofenadine 60 Mg Oral TabletPlacebo

Brief Summary

The goal of this study is o evaluate the prognostic effect of fexofenadine hydrochloride in patients with myocardial infarction

Eligibility Criteria

Inclusion Criteria: * Age ≥ 18 years old. * Able to verbally confirm understanding of the trial risks, benefits, and treatment options of fexofenadine hydrochloride therapy. He/she or his/her legal representative must provide written informed consent prior to participating in the clinical trial. * Acute ST-segment elevation myocardial infarction (STEMI) occurring within 7 days, with diagnostic criteria including: i) Typical clinical symptoms: such as severe crushing pain in the retrosternal or precordial area, usually lasting more than 10-20 minutes, which may radiate to the left upper arm, jaw, neck, back, or shoulders, etc.; ii) Elevated serum cardiac troponin (cTn): at least one measurement above the upper limit of normal (99th percentile of the reference upper limit); iii) ST-segment elevation: new ST-segment elevation at the J point in 2 adjacent leads. * Echocardiography indicating segmental wall motion abnormalities. Exclusion Criteria: * Need for long-term use of fexofenadine h

Related Trials