NCT06882733 The Immediate Effect of Applying Transcutaneous Electrical Nerve Stimulation (TENS) on Sympathetic Ganglion and Gastrocnemius for Popliteal Blood Flow
| NCT ID | NCT06882733 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kaohsiung Medical University |
| Condition | Transcutaneous Electrical Nerve Stimulation (TENS) |
| Study Type | INTERVENTIONAL |
| Enrollment | 43 participants |
| Start Date | 2024-12-03 |
| Primary Completion | 2025-03-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 43 participants in total. It began in 2024-12-03 with a primary completion date of 2025-03-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the immediate hemodynamic effects of transcutaneous electrical nerve stimulation (TENS) on the popliteal artery and vein. Vascular issues like PAOD and DVT are common in patients with diabetes, obesity, or immobility due to increased resistance and reduced blood flow. Traditional treatments (medication or surgery) are not always feasible, prompting interest in TENS as an alternative. Although primarily used for pain relief, TENS may enhance blood flow. This research compares different stimulation frequencies (80 Hz vs. 4 Hz) and sites (gastrocnemius muscle vs. thoracolumbar sympathetic ganglia) to identify the most effective configuration.
Eligibility Criteria
Inclusion Criteria: 1. Healthy people 2. Age: 18 years and above (inclusive) 3. Body mass index (BMI) between 18.5 and 24 Exclusion Criteria: 1. Unable to complete two interventions within a week 2. Have contraindications to electrotherapy (for example: metal implants in the body, open wounds, pregnancy, sensory loss) 3. Obvious varicose veins 4. Unable to lie down for about 1 to 2 hours 5. Taking drugs or nutritional supplements that affect autonomic nervous activity or vasodilation (for example: Ginkgo biloba) 6. Smoking 7. Ankle and Ankle Index (ABI) less than 0.9 or greater than 1.3
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06882733 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Transcutaneous Electrical Nerve Stimulation (TENS). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06882733 currently recruiting?
Yes, NCT06882733 is actively recruiting participants. Contact the research team at mengjie910419@gmail.com for enrollment information.
Where is the NCT06882733 trial being conducted?
This trial is being conducted at Kaohsiung City, Taiwan.
Who is sponsoring the NCT06882733 clinical trial?
NCT06882733 is sponsored by Kaohsiung Medical University. The trial plans to enroll 43 participants.