| NCT ID | NCT03303833 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Wageningen University |
| Condition | Lynch Syndrome |
| Study Type | OBSERVATIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2006-07-01 |
| Primary Completion | 2030-12 |
Trial Parameters
Eligibility Fast-Check
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Brief Summary
The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.
Eligibility Criteria
Inclusion Criteria: * Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene. * Aged between 18 and 80 years at inclusion. Exclusion Criteria: * Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP) * (Chronic) Inflammatory bowel disease * Non-Dutch speaking * Dementia or another mental condition that makes it impossible to fill out questionnaires * Terminally ill persons