NCT07113652 The Efficacy of Temporal Interference Stimulation in the Treatment of Obsessive-Compulsive Disorder
| NCT ID | NCT07113652 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Shanghai Mental Health Center |
| Condition | Obsessive-Compulsive Disorder (OCD) |
| Study Type | INTERVENTIONAL |
| Enrollment | 18 participants |
| Start Date | 2025-08-17 |
| Primary Completion | 2027-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 18 participants in total. It began in 2025-08-17 with a primary completion date of 2027-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate the efficacy of Temporal Interference (TI) stimulation in treating patients with obsessive-compulsive disorder (OCD) and to explore its potential neural mechanisms using magnetic resonance imaging (MRI) and electroencephalography (EEG).
Eligibility Criteria
Inclusion Criteria: * 18-50 years old * Diagnosis of OCD per DSM-5 * Y-BOCS score ≥20 * Have a documented history of at least two adequate trials of selective serotonin reuptake inhibitors (SSRIs). If currently receiving SSRI treatment, the dosage must be stable for at least 8 weeks prior to enrollment * With at least 9 years of education Exclusion Criteria: * Any DSM-5 diagnosis other than OCD (except OCPD) * OCD symptoms too severe to complete assessments * Received electroconvulsive therapy (ECT) within the past 6 months * Received other forms of neuromodulation within the past 2 months（see Item 3 for ECT） * Severe medical illness or seizure risk (e.g., cardiovascular, respiratory conditions) * Neurological disorders or history of brain injury/surgery * MRI-incompatible implants (e.g., pacemaker, stents, cochlear implants). * Current suicidal risk per investigator judgment * Pregnant or planning pregnancy during the study * Started structured OCD psychotherapy within 3 months, with expected change during treatment
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07113652 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 50 Years, studying Obsessive-Compulsive Disorder (OCD). Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07113652 currently recruiting?
Yes, NCT07113652 is actively recruiting participants. Contact the research team at wangzhen@smhc.org.cn for enrollment information.
Where is the NCT07113652 trial being conducted?
This trial is being conducted at Shanghai, China.
Who is sponsoring the NCT07113652 clinical trial?
NCT07113652 is sponsored by Shanghai Mental Health Center. The trial plans to enroll 18 participants.