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Recruiting NCT05474417

NCT05474417 The Effects of the CF Carrier State on the Kidneys and Pancreas

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Clinical Trial Summary
NCT ID NCT05474417
Status Recruiting
Phase
Sponsor Philip Polgreen
Condition Carrier State
Study Type OBSERVATIONAL
Enrollment 1,250 participants
Start Date 2021-12-20
Primary Completion 2026-07

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 100 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,250 participants in total. It began in 2021-12-20 with a primary completion date of 2026-07.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The overarching hypothesis is that CF carriers are at increased risk for developing most of the extrapulmonary conditions associated with CF compared to the general population. Specifically, it is hypothesized that this pilot data will detect subclinical evidence of pancreatic and kidney disorders among CF carriers. This will be determined by bringing CF carriers and controls to the CRU for one visit where they will answer survey questions and undergo laboratory testing. Additionally, they will collect urine and stool samples at home that will be sent to outside laboratories for testing.

Eligibility Criteria

CF Carrier Inclusion Criteria: * A CF Carrier identified via genetic testing Control Inclusion Criteria: * No previous CF carrier test results Exclusion Criteria: * CF patient status * Unable to speak English * Currently pregnant * Unable to provide written informed consent * Prisoner status * Currently taking any medications for the treatment of diabetes

Contact & Investigator

Central Contact

Philip M Polgreen, MD

✉ philip-polgreen@uiowa.edu

📞 (319) 384-6194

Principal Investigator

Philip M Polgreen, MD

PRINCIPAL INVESTIGATOR

University of Iowa

Frequently Asked Questions

Who can join the NCT05474417 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Carrier State. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05474417 currently recruiting?

Yes, NCT05474417 is actively recruiting participants. Contact the research team at philip-polgreen@uiowa.edu for enrollment information.

Where is the NCT05474417 trial being conducted?

This trial is being conducted at Iowa City, United States.

Who is sponsoring the NCT05474417 clinical trial?

NCT05474417 is sponsored by Philip Polgreen. The principal investigator is Philip M Polgreen, MD at University of Iowa. The trial plans to enroll 1,250 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology