NCT05075005 The Effects of Terrain Variation on Intrinsic Foot Musculature in Healthy Individuals and Individuals With Plantar Fasciitis
| NCT ID | NCT05075005 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Florida |
| Condition | Plantar Fasciitis |
| Study Type | INTERVENTIONAL |
| Enrollment | 60 participants |
| Start Date | 2024-09-15 |
| Primary Completion | 2027-01-20 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 60 participants in total. It began in 2024-09-15 with a primary completion date of 2027-01-20.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Modern footwear has been implicated as a contributor to foot pathology and changes in the biomechanics of gait. In addition to footwear, the investigators propose that the lack of terrain variation may directly contribute to the development of common foot pathologies, resulting from decreased intrinsic foot muscle function. This study will examine the current understanding of terrain variation on foot musculature strength and its possible correlation with structural and functional changes within the foot.
Eligibility Criteria
Inclusion Criteria for Group A: * Patients presenting to the University of Florida Orthopaedics and Sports Medicine Institute with pain on the plantar medial or central heel for greater than 60 days with the following features * Pain upon palpation, or insidious pain onset * Pain accentuated after long periods of weight bearing activities or after periods of rest * A reduction in pain following light activities (McPoil et al., 2008) * Failure to respond to treatment modalities for 6 months, including plantar fascia and muscle stretching, nonsteroidal anti-inflammatory medication, supportive insoles, and night splints * Age \>18 years Inclusion Criteria for Group B: * Healthy individuals in the general population of Gainesville and surrounding areas * Age \>18 Exclusion Criteria for Group A: * History of lower leg or foot surgery, hindfoot trauma or fracture of the affected limb within the previous year. * Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease, Achilles tendinopathy, metatarsalgia, tarsal tunnel syndrome or heel pad syndrome * Body Mass Index (BMI) \> 35 * Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter * Third trimester pregnancy Exclusion Criteria for Group B: * Any foot or lower limb pathology resulting in discomfort or gait limitation * Diagnosis of diabetic neuropathy, fibromyalgia, neurological disease * BMI \>35 * Currently taking or applying any anti-inflammatory medication or medication to control nerve pathology, prescription or over the counter * Third trimester pregnancy
Contact & Investigator
Antony Merendino, DPM
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT05075005 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 100 Years, studying Plantar Fasciitis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05075005 currently recruiting?
Yes, NCT05075005 is actively recruiting participants. Contact the research team at merena@ortho.ufl.edu for enrollment information.
Where is the NCT05075005 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT05075005 clinical trial?
NCT05075005 is sponsored by University of Florida. The principal investigator is Antony Merendino, DPM at University of Florida. The trial plans to enroll 60 participants.