NCT05112328 The Effects of Pancreatic Enzyme Supplementation in Critically Ill Patients on Enteral Feeding
| NCT ID | NCT05112328 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Seoul National University Hospital |
| Condition | Critically Ill |
| Study Type | INTERVENTIONAL |
| Enrollment | 170 participants |
| Start Date | 2021-07-07 |
| Primary Completion | 2026-07-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 170 participants in total. It began in 2021-07-07 with a primary completion date of 2026-07-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Determine the effect of high-dose pancreatic enzyme supplementation on nutritional indicators and clinical course in critically ill patients undergoing enteral nutrition.
Eligibility Criteria
Inclusion Criteria: * Adults 19 years and older * Hospitalized in the surgical/medical intensive care unit of the Seoul National University Hospital * Enteral nutrition * Patients who consented to this study * Patients with risk factors for pancreatic exocrine dysfunction * Shock (Norepinephrine) * Sepsis (3 rd definition of sepsis) * Diabetes * Cardiac arrest * hyperlactatemia serum lactate \> 2 mmol/L) * Mechanical ventilation * Continuous renal replacement therapy Exclusion Criteria: * chronic pancreatitis * unresectable pancreatic cancer * History of pancreatectomy * Underlying diseases in which the effect of Exocrine pancreatic enzyme administration is difficult to show * Inflammatory bowel disease * Short bowel syndrome
Contact & Investigator
Frequently Asked Questions
Who can join the NCT05112328 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Critically Ill. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05112328 currently recruiting?
Yes, NCT05112328 is actively recruiting participants. Contact the research team at faun1226@gmail.com for enrollment information.
Where is the NCT05112328 trial being conducted?
This trial is being conducted at Seoul, South Korea.
Who is sponsoring the NCT05112328 clinical trial?
NCT05112328 is sponsored by Seoul National University Hospital. The trial plans to enroll 170 participants.