NCT06660706 The Effects of Exercise Intervention on Skeletal Muscle and Other Organs in Aged Population and the Discovery of Associated Circulating Biomarkers
| NCT ID | NCT06660706 |
| Status | Recruiting |
| Phase | — |
| Sponsor | National Yang Ming Chiao Tung University |
| Condition | Age-related Functional Decline |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2024-04-01 |
| Primary Completion | 2026-06 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2024-04-01 with a primary completion date of 2026-06.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This project aims to investigate the intricate interplay between skeletal muscle and adipose tissue during the aging process by integrating human studies. Utilizing interventional research and randomized trials combined with examining blood samples from elderly individuals engaged in exercise, we aim to investigate the effects of exercise on muscle health and explore the underlying mechanisms of muscle aging and related biomarkers. Interdisciplinary research allowed us to investigate the systemic impact of exercise on muscles. This approach allowed us to gain a better understanding of the interconnectedness of skeletal muscle and adipose tissue in the aging process and devise efficient strategies to reverse age-related changes. These findings hold promise for promoting a future society where long and healthy life is achievable for all.
Eligibility Criteria
Inclusion Criteria: * aged ≥ 65 years * slow gait speed (\<1 m/s in 6-meter walk test) or weakness (dominant handgrip strength \<28 kg in men, \<18 kg in women) Exclusion Criteria: * established diagnosis of dementia, Parkinsonism or other mobility-limiting, disable conditions * active, acute diseases receiving treatment, such as cancer, heart failure, COPD and so on * estimated life expectancy \<12 months * current nursing home residents
Contact & Investigator
Li-Ning Peng, M.D., PhD
PRINCIPAL INVESTIGATOR
Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University
Frequently Asked Questions
Who can join the NCT06660706 clinical trial?
This trial is open to participants of all sexes, aged 65 Years or older, studying Age-related Functional Decline. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06660706 currently recruiting?
Yes, NCT06660706 is actively recruiting participants. Contact the research team at lining.peng@gmail.com for enrollment information.
Where is the NCT06660706 trial being conducted?
This trial is being conducted at Taipei, Taiwan.
Who is sponsoring the NCT06660706 clinical trial?
NCT06660706 is sponsored by National Yang Ming Chiao Tung University. The principal investigator is Li-Ning Peng, M.D., PhD at Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University. The trial plans to enroll 100 participants.