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Recruiting NCT06514729

The Effects of Different Ventilation Modes on Patients With Pulmonary Lobe Resection

Trial Parameters

Condition Lung Injury
Sponsor Mao Enting
Study Type INTERVENTIONAL
Phase N/A
Enrollment 102
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2024-01-01
Completion 2025-05
Interventions
Adopting different ventilation modes during the operation

Brief Summary

The objective of this study was to discuss the effects of different ventilation modes on patients with plasma inflammatory factor and respiratory function in patients with pulmonary removal.

Eligibility Criteria

Inclusion Criteria: Comprehensive examination and analysis of imaging, laboratory examination and other comprehensive examinations, the diagnosis is clear, which is in line with lobe resection surgical indications Age 18-75 years old, the gender is not limited; ASA grading Ⅰ \~ III level; It is expected that the single lung ventilation time is ≥1 hours, and ≤3 hours Exclusion Criteria: Emergency surgery; There is a taboos on the existence of systemic anesthesia; There is a history of acute chronic upper respiratory infections in the past January; Previous bronchial asthma, chronic obstructive pulmonary disease, bronchial dilatation, phthisis ,aspergillosis , acute respiratory distress syndrome or history of respiratory failure; Merge the function of important organs such as heart, liver, and kidney; There was a history of chest surgery and the history of trauma; Preoperative lung function test obvious abnormal abnormal abnormalities (1 second of exhalation (FEV1) \<60%); Patients refus

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