The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
Trial Parameters
Brief Summary
This study was a single-center RCT study to compare the effect of preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon with that of traditional treatment in patients with bowel function after stoma closure.
Eligibility Criteria
Inclusion Criteria: * aged 18-85 years old * Karnofsky performance status (KPS)≥70%; Or ECOG score 2 points or less * rectal cancer confirmed by preoperative pathology * in the rectum resection before low, low colorectal anastomosis or after neoadjuvant therapy of patients * prophylactic ileostomy. Exclusion Criteria: * cannot complete treatment * the history of the anorectal surgery * preoperative bowel dysfunction such as diarrhea, irritable bowel syndrome and functional constipation, etc.) * postoperative anastomotic fistula and stricture * during pregnancy or breastfeeding women * with uncontrolled seizures, central nervous system disease or a history of mental disorders * the last five years have other history of malignant disease cured except skin cancer and cervical carcinoma in situ * clinically significant (i.e., active) heart disease, such as symptomatic coronary artery disease, New York Heart Association class II or worse 9) severe congestive heart failure or major arrhythmi